Would you like email updates of new search results? Polymorphic light eruption is a fairly common skin rash triggered by exposure to sunlight or artificial ultraviolet (UV) light. Majoie IML, van Weelden H, Sybesma IM, Coenraads PJ, Sigurdsson V. Polymorphous light eruption-like skin lesions in welders caused by ultraviolet C light. It is also known as polymorphous light eruption, sun allergy, sun poisoning, prurigo aestivalis, summer eruption/prurigo, or eczema solare. [2], Recurring yearly, the eruption can sometimes last longer than a few days if persistent and repeated sun exposure occurs. Polymorphous light eruption (PLE) is a common skin rash that occurs due to sunlight exposure. None are generally needed. Mayo Clinic. Read on to learn more about how PMLE might affect you and what you can do about it. arrow-right-small-blue What treatments are available, and which do you recommend? Last reviewed by a Cleveland Clinic medical professional on 02/20/2023. J Am Acad Dermatol. It is most often found in females in the second or third decade of life and occurs in 10-15% of the U.S. population. There are many clothing choices that can help you do this, such as: Polymorphous light eruption is a condition that causes your skin to react to light, usually UV light. Skin biopsy shows upper dermal edema, and a dense perivascular and periadnexal lymphocytic infiltrate without vasculitis. It may affect up to 15% of people worldwide. Polymorphic light eruption pathology Your health care provider can probably make a diagnosis of polymorphous light eruption based on a physical exam and your answers to questions. It is more common in patients who receive only intermittent sun exposure and typically consists of crops of papules, vesicles or plaques. Sunscreens. This site needs JavaScript to work properly. Accurate diagnosis relies on the exclusion of other photosensitive conditions. arrow-right-small-blue Thus, a patient may benefit from a mental health counsultant. Sunburn reaction in patients affected by polymorphous light eruption is normal. [6], People vary in the amount of sun exposure needed to trigger the rash. Polymorphous light eruption is generallyuncomplicated but severe disease can lead to emotional distress, anxiety and depression. J Invest Dermatol. Learn more here. These healthcare professionals should educate the patients on preventio which includes wearing appropriate garments when going outside and use ample sunscreen frequently. Can you prevent polymorphous light eruption? [2] However, the "hardening" effect, with respite during the later summer, frequently occurs with gradual exposure of sunlight,[5] eventually leading to significant improvement. There is a phenomenon called the skin hardening effect where chronic exposure to sunlight leads to skin changes including increased melanin and thickening of the stratum corneum. Your skin can build up a tolerance to UV light throughout the summer, but this will go away during the winter. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Polymorphous light eruption is typically diagnosed with a thorough health history and skin examination. Polymorphous means it looks different in different people. Spongiosis and vesicle formation may also be present. Sometimes, these papules appear in a dense formation, making the rash look similar to eczema or prickly heat. Endogenous estrogen exacerbates UV-induced inflammation and photoaging in mice. Polymorphous light eruption is a common photosensitive reaction to UV and sometimes visible light. Join. If you have any concerns with your skin or its treatment, see a dermatologist for advice. Elsevier; 2021. https://www.clinicalkey.com. To exclude other photosensitive conditions a skin biopsy may be considered. This morning, I did my hyaluronic acid serum on very damp skin and did my CeraVe Eye Repair Cream. 2018 Jun; [PubMed PMID: 29430717], Choi D,Kannan S,Lim HW, Evaluation of patients with photodermatoses. The eruption appears first on limited areas, but becomes more extensive during subsequent summers. Murphy F, et al. PMLE affects all ages, sexes, races and ethnicities. This site needs JavaScript to work properly. Photodermatology, photoimmunology [PubMed PMID: 30267642], Rossi MT,Arisi M,Lonardi S,Lorenzi L,Ungari M,Serana F,Fusano M,Moggio E,Calzavara-Pinton PG,Venturini M, Cutaneous infiltration of plasmacytoid dendritic cells and T regulatory cells in skin lesions of polymorphic light eruption. When? The reaction usually happens during spring and early summer when exposure to sunlight increases. It may persist for weeks or months if repeatedly exposed, although in most individuals gradual exposure leads to hardening so that the eruption does not occur in late summer. The epidermal changes range from being almost normal to showing impressive spongiosis and acanthosis. This can explain why it is uncommon to get PMLE in areas of the face or hands due to their chronic exposure to the sun compared to other areas of the body. Despite the fact that polymorphous light eruption (PLE) is the most common photodermatosis, affecting 15% of healthy people in the UK, its pathogeny remains unclear. For utmost sun protection, use your sunscreen before the stated expiration date. Dark lips are often the result of hyperpigmentation. Theories must account for increased prevalence in women and for the hardening effect of on-going exposure to ultraviolet radiation. Symptoms of polymorphic light eruption An itchy or burning rash appears within hours, or up to 2 to 3 days after exposure to sunlight. PMLE is generally treatable with both home remedies and medical interventions. Insight into immunocytes infiltrations in polymorphous light eruption. Fig. doi:10.1111/j.1365-2133.1989.tb07781.x. polymorphic-light-eruption. Cream! It looks like reddened skin with raised red spots or small blisters. Broad-spectrum sunscreens provide better protection from solar ultraviolet-simulated radiation and natural sunlight-induced immunosuppression in human beings. ", "Unique profile of antimicrobial peptide expression in polymorphic light eruption lesions compared to healthy skin, atopic dermatitis, and psoriasis", "Disease associations in polymorphous light eruption. Polymorphous light eruption is a rash caused by sun exposure in people who have developed sensitivity to sunlight. ncbi.nlm.nih.gov/pmc/articles/PMC7379702/, ncbi.nlm.nih.gov/pmc/articles/PMC8323194/, ncbi.nlm.nih.gov/pmc/articles/PMC6139322/, dermnetnz.org/topics/polymorphic-light-eruption, nhs.uk/conditions/polymorphic-light-eruption/, aad.org/public/everyday-care/sun-protection/shade-clothing-sunscreen/what-to-wear-protect-skin-from-sun, Every Sunscreen Question You Have, Answered, Debra Sullivan, Ph.D., MSN, R.N., CNE, COI. An official website of the United States government. Its the most common skin condition caused by sunlight. 2010;130(2):6268. Polymorphous light eruption (PMLE) is a common skin rash that develops in people who are sensitive to ultraviolet (UV) light. Experts have suggested it may also be at least partly associated with: While the causes of PMLE are still under investigation, the rash is brought on by UV light. This exposes the skin to small doses of UVA or UVB light that helps your skin be less sensitive to light. You should reapply every 2 hours. Polymorphic Light Eruption (PLE) (also known as polymorphous light eruption and benign summer light eruption) is a recurrent, itchy skin eruption occurring on exposed skin sites after sun exposure, which heals without scarring within 14 days ().The presenting skin eruption is most commonly spots and blisters but may also take other forms, including plaques (raised . People living with PMLE should avoid exposure to sunlight, especially between 11 a.m. and 3 p.m., when UV rays are strongest. It occurs most often on areas of skin that haven't seen the sun for a while - it is more common on the arms and the . Additionally, the AAD suggests covering your skin from direct sun exposure. However, positive antinuclear antibody and extractable nuclear antigen (anti-Ro/La) in low titre may be found, even in the absence of other criteria to suggest a diagnosis of lupus erythematosus. Prevention of Polymorphic Light Eruption Afforded by a Very High Broad-Spectrum Protection Sunscreen Containing Ectoin. Photochemical [PubMed PMID: 22961505], Richards HL,Ling TC,Evangelou G,Brooke RC,Fortune DG,Rhodes LE, Evidence of high levels of anxiety and depression in polymorphic light eruption and their association with clinical and demographic variables. [2] Due to its many clinical appearances, it is named polymorphic or polymorphous and the terms are used interchangeably. [2] When a decision to undertake this is made, a small area of the frequently affected skin is exposed to varying doses of UVA and minimal erythema dose (MED) (amount of UV radiation that will produce minimal redness of skin within a few hours following exposure)[2][17] of broadband UVB for three consecutive days. American Academy of Dermatology. Books about skin diseasesBooks about the skin This condition causes a red, itchy rash to form soon after youve been in the sun or exposed to artificial UV rays. Idiopathic photodermatosis; Immunomediated photodermatosis; Minimal erythema dose; Photoprovocation tests; Phototests; Polymorphous light eruption; UV light. //]]>. The rash most commonly appears on your: Juvenile spring eruption is a type of PMLE that tends to affect the ears of children (mostly boys). Histology of PMLE. If the symptoms have a clear connection to sun exposure, the doctor may base a diagnosis on this. But is jock itch contagious? The cause of polymorphic light eruption is unknown. Br J . Polymorphic light eruption: an immunopathological study of evolving lesions. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). PMLE is characterized by recurrent, abnormal, delayed reactions to sunlight, ranging from erythematous papules, papulovesicles, and plaques to erythema multiforme -like lesions on sunlight-exposed surfaces. White spots on your nipples are usually harmless. Polymorphic light eruption is the most common form of immunologically mediated photosensitivity dermatoses. Up to 20% of people live with this problem. If they are not sure, they may suggest a skin biopsy. The rash persists for several days then clears up without scarring if further exposure to UV is avoided. Consider wearing clothing designed to provide sun protection. Centers for Disease Control and Prevention (CDC). PMLE is not contagious. Eruption refers to the sudden onset of the rash, usually within 30 minutes of UV light exposure. In up to 50% of cases, people with PLE have family members who also have the condition. There are often lymphocytes in the epidermis (exocytosis, figure 3). Norris PG, Morris J, McGibbon DM, Chu AC, Hawk JL. Accessed Dec. 9, 2021. You can learn more about how we ensure our content is accurate and current by reading our. J Invest Dermatol. Lesions may vary from patient to patient; however, spontaneous resolution (on cessation of sun exposure) is often a unifying trait. It also occurs more frequently in places that are at higher altitudes and in more temperate climates. sharing sensitive information, make sure youre on a federal [7] The resulting itch can cause significant suffering. There may also be a link with estrogen, according to the 2022 review. The eruption can appear within hours of sun exposure and last for days. What Causes White Spots to Form on Your Nipple? Individual patients tend to develop the same type and pattern of outbreak each year. Anyone can have PMLE, but its more common for people with lighter color skin, particularly Fitzpatrick skin type 1. 2014;22:24. Polymorphic light eruption codes and concepts, 238525001, 79372000, 238525001, 6618004, 54116000, 84036008, 51048002. Description of the condition. The condition is more frequent in females and begins often in young adults and in mid-adult life. The role of diet in treating PLE requires more research. Using high SPF, broad-spectrum sunscreen, and wearing protective clothing helps minimize UV light exposure. FOIA 2. While the rash varies from person to person, the particular rash you get will typically be similar every time it happens. People who live where sun exposure is uncommon. Kittler H, Hnigsmann H, Tanew A: Antinuclear antibodies in patients with polymorphic light eruption: a long-term follow-up study. This roundup covers our top picks for best scar creams, from the best overall to creams for postsurgery, old scars, and fading discoloration. Polymorphic light eruption (PMLE) is a seasonal, acquired, idiopathic photodermatosis occurring in spring and early summer. Dermatologic clinics. Plasmacytoid dendritic cells and T regulatory cells predominate. The site is secure. //